Acetate → 2-Chloro-8-(2-methoxy-phenyl)-[1,2,4]triazolo[1,5-a]pyridine
Reaction equation
[Br:20][c:21]1[c:22]2[n:23]([cH:24][cH:25][cH:26]1)[n:27][c:28]([Cl:30])[n:29]2.[C:52]([O-:53])(=[O:54])[CH3:55].[C:57]([O-:58])(=[O:59])[CH3:60].[CH2:66]1[O:67][CH2:68][CH2:69][O:70][CH2:71]1.[CH3:31][O:32][c:33]1[c:34]([B:39]([OH:40])[OH:41])[cH:35][cH:36][cH:37][cH:38]1.[CH3:61][N:62]([CH3:63])[CH:64]=[O:65].[Cl:49][CH2:50][Cl:51].[Na+:42].[Na+:43].[O-:44][C:45](=[O:46])[O-:47].[OH2:48].[Pd+2:56].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[c:21]1(-[c:34]2[c:33]([O:32][CH3:31])[cH:38][cH:37][cH:36][cH:35]2)[c:22]2[n:23]([cH:24][cH:25][cH:26]1)[n:27][c:28]([Cl:30])[n:29]2Participants
12
Reactant 11
HCID 175Acetate2×
HCID 923Sodium ion2×
HCID 962Water
HCID 6228Dimethylformamide
HCID 6344Dichloromethane
HCID 11776Triphenylphosphine
HCID 19660Carbonate Ion
HCID 312751,4-Dioxane
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 27339582-Methoxyphenylboronic acid
HCID 674813708-Bromo-2-chloro-[1,2,4]triazolo[1,5-a]pyridineProduct 1
Sources & evidence
- ORD record
- ord-6d2595f0cfba4301afa885fa5471e60a
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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