Dimethylformamide → tert-butyl N-[7a-[5-[(5-bromopyridine-2-carbonyl)amino]-2-fluorophenyl]-4,4a,5,6-tetrahydrofuro[2,3-d][1,3]thiazin-2-yl]carbamate

HRID 835196Notes

Reaction equation

[Br:26][c:27]1[cH:28][cH:29][c:30]([C:33](=[O:34])[OH:35])[n:31][cH:32]1.[CH:60]([N:61]([CH2:62][CH3:63])[CH:64]([CH3:65])[CH3:66])([CH3:67])[CH3:68].[NH2:1][c:2]1[cH:3][cH:4][c:5]([F:25])[c:6]([C:8]23[N:9]=[C:10]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[S:11][CH2:12][CH:13]2[CH2:14][CH2:15][O:16]3)[cH:7]1.[O:69]=[CH:70][N:71]([CH3:72])[CH3:73].[P-:36]([F:37])([F:38])([F:39])([F:40])([F:41])[F:42].[n:43]1([O:44][C:45]([N:46]([CH3:47])[CH3:48])=[N+:49]([CH3:50])[CH3:51])[c:52]2[n:53][cH:54][cH:55][cH:56][c:57]2[n:58][n:59]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([F:25])[c:6]([C:8]23[N:9]=[C:10]([NH:17][C:18]([O:19][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:24])[S:11][CH2:12][CH:13]2[CH2:14][CH2:15][O:16]3)[cH:7]1)[C:33]([c:30]1[cH:29][cH:28][c:27]([Br:26])[cH:32][n:31]1)=[O:34]