Trifluoroacetic acid → 5-(2-Chloroethyl)-6-chlorooxindole

HRID 835969Notes

Reaction equation

HRID 835969 reaction equation
[CH2:16]([SiH:17]([CH2:18][CH3:19])[CH2:20][CH3:21])[CH3:22].[Cl:1][c:2]1[c:3]([CH:12]([CH2:13][Cl:14])[OH:15])[cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[CH2:6]2.[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[Cl:1][c:2]1[c:3]([CH2:12][CH2:13][Cl:14])[cH:4][c:5]2[c:9]([cH:10]1)[NH:8][C:7](=[O:11])[CH2:6]2

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 12052TriethylsilaneHCID 16128890HCID 16128890, compound

Product 1

HCID 106094745-(2-Chloroethyl)-6-chlorooxindole

Sources & evidence

ORD record
ord-b39df3cf4950411d93e05b2d5e8e5e56
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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