Trifluoroacetic acid → 5-Fluoro-1,2,3,4-tetrahydroquinoline

HRID 836557Notes

Reaction equation

HRID 836557 reaction equation
[CH2:20]([SiH:21]([CH2:22][CH3:23])[CH2:24][CH3:25])[CH3:26].[F:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[NH:7][CH2:6][CH2:5][C:4]2=[O:12].[OH:13][C:14]([C:15]([F:16])([F:17])[F:18])=[O:19]>>[F:1][c:2]1[c:3]2[c:8]([cH:9][cH:10][cH:11]1)[NH:7][CH2:6][CH2:5][CH2:4]2

Participants

4

Reactant 3

HCID 6422Trifluoroacetic acidHCID 12052TriethylsilaneHCID 55297457HCID 55297457, compound

Product 1

HCID 162443815-Fluoro-1,2,3,4-tetrahydroquinoline

Sources & evidence

ORD record
ord-3037dec6ed4d43d59d0decfdb680a971
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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