Dichloromethane → 4,6-Dimethoxy-pyrimidin-2-carbothioic acid amide

HRID 836815Notes

Reaction equation

HRID 836815 reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][CH2:50]1.[CH3:14][O:15][c:16]1[cH:17][cH:18][c:19]([P:20]2(=[S:23])[S:21][P:22]([c:24]3[cH:25][cH:26][c:27]([O:28][CH3:29])[cH:30][cH:31]3)(=[S:32])[S:33]2)[cH:34][cH:35]1.[CH3:1][O:2][c:3]1[n:4][c:5]([C:11](=[O:12])[NH2:13])[n:6][c:7]([O:9][CH3:10])[cH:8]1.[CH:39]([O:40][CH:41]([CH3:42])[CH3:43])([CH3:44])[CH3:45].[Cl:36][CH2:37][Cl:38]>>[CH3:1][O:2][c:3]1[n:4][c:5]([C:11]([NH2:13])=[S:23])[n:6][c:7]([O:9][CH3:10])[cH:8]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 7914Diisopropyl EtherHCID 8028TetrahydrofuranHCID 87949Lawesson's reagentHCID 582826824,6-Dimethoxypyrimidin-2-carboxylic acid amide

Product 1

HCID 582827014,6-Dimethoxy-pyrimidin-2-carbothioic acid amide

Sources & evidence

ORD record
ord-c1ad394e833a49f5a4e7ccca7dcffa02
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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