Tetrahydrofuran → 4-amino-N-(1-ethyl-4-piperidyl)-3-methoxy-benzamide

HRID 836846Notes

Reaction equation

HRID 836846 reaction equation
[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[NH2:22][CH:23]1[CH2:24][CH2:25][N:26]([CH2:29][CH3:30])[CH2:27][CH2:28]1.[O:38]1[CH2:39][CH2:40][CH2:41][CH2:42]1.[n:1]1([O:2][C:11]([c:12]2[cH:13][c:14]([O:19][CH3:20])[c:15]([NH2:18])[cH:16][cH:17]2)=[O:21])[c:3]2[cH:4][cH:5][cH:6][cH:7][c:8]2[n:9][n:10]1>>[C:11]([c:12]1[cH:13][c:14]([O:19][CH3:20])[c:15]([NH2:18])[cH:16][cH:17]1)(=[O:21])[NH:22][CH:23]1[CH2:24][CH2:25][N:26]([CH2:29][CH3:30])[CH2:27][CH2:28]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 37349901-Ethylpiperidin-4-amineHCID 106606854-Amino-3-methoxy-benzoic acid benzotriazol-1-yl ester

Product 1

HCID 580150934-amino-N-(1-ethyl-4-piperidyl)-3-methoxy-benzamide

Sources & evidence

ORD record
ord-7cb946b5172d4af2b55977b476d2bc17
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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