2-Aminothiazole → 3-[2-(4-Fluoro-phenyl)-pyrimidin-5-yl]-N-(thiazol-2-yl)-acrylamide

HRID 837009Notes

Reaction equation

[CH3:49][CH2:50][N:51]([CH2:52][CH3:53])[CH2:54][CH3:55].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([CH:14]=[CH:15][C:16](=[O:17])[OH:18])[cH:12][n:13]2)[cH:6][cH:7]1.[NH2:19][c:20]1[s:21][cH:22][cH:23][n:24]1.[P-:25]([F:26])([F:27])([F:28])([F:29])([F:30])[F:31].[n:32]1([O:33][C:34]([N:35]([CH3:36])[CH3:37])=[N+:38]([CH3:39])[CH3:40])[c:41]2[n:42][cH:43][cH:44][cH:45][c:46]2[n:47][n:48]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][cH:10][c:11]([CH:14]=[CH:15][C:16](=[O:18])[NH:19][c:20]3[s:21][cH:22][cH:23][n:24]3)[cH:12][n:13]2)[cH:6][cH:7]1