Potassium Cation → Tert-butyl 4-(2-methoxyethoxy)piperidin-1-carboxylate

HRID 837332Notes

Reaction equation

HRID 837332 reaction equation
[Br:15][CH2:16][CH2:17][O:18][CH3:19].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([OH:14])[CH2:12][CH2:13]1.[H-:22].[I-:21].[K+:20].[Na+:23].[O:24]=[CH:25][N:26]([CH3:27])[CH3:28]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][CH2:16][CH2:17][O:18][CH3:19])[CH2:12][CH2:13]1

Participants

8

Reactant 7

HCID 813Potassium CationHCID 923Sodium ionHCID 6228DimethylformamideHCID 30165Iodide IonHCID 809722-Bromoethyl methyl etherHCID 166653HydrideHCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

Product 1

HCID 57476927Tert-butyl 4-(2-methoxyethoxy)piperidin-1-carboxylate

Sources & evidence

ORD record
ord-3911841b841648659974d3b61a34a15a
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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