Acetate → γ-Methylene-6-quinolinepropanol
Reaction equation
[Br:20][C:21]([CH2:22][CH2:23][OH:24])=[CH2:25].[C:69]([O-:70])(=[O:71])[CH3:72].[C:74]([O-:75])(=[O:76])[CH3:77].[CH3:1][C:2]1([CH3:3])[C:4]([CH3:5])([CH3:6])[O:7][B:8]([c:9]2[cH:10][c:11]3[cH:12][cH:13][cH:14][n:15][c:16]3[cH:17][cH:18]2)[O:19]1.[CH3:55][c:56]1[cH:57][cH:58][cH:59][cH:60][cH:61]1.[CH3:63][CH2:64][O:65][C:66]([CH3:67])=[O:68].[CH:26]1([P:27]([CH:28]2[CH2:29][CH2:30][CH2:31][CH2:32][CH2:33]2)[c:34]2[cH:35][cH:36][cH:37][cH:38][c:39]2-[c:40]2[c:41]([O:42][CH3:43])[cH:44][cH:45][cH:46][c:47]2[O:48][CH3:49])[CH2:50][CH2:51][CH2:52][CH2:53][CH2:54]1.[OH2:62].[Pd+2:73]>>[c:9]1([C:21]([CH2:22][CH2:23][OH:24])=[CH2:25])[cH:10][c:11]2[cH:12][cH:13][cH:14][n:15][c:16]2[cH:17][cH:18]1Participants
9
Reactant 8
HCID 175Acetate2×
HCID 962Water
HCID 1140Toluene
HCID 8857Ethyl Acetate
HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)
HCID 5339753-Bromo-3-buten-1-ol
HCID 112698722-Dicyclohexylphosphino-2',6'-dimethoxybiphenyl
HCID 162177846-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolineProduct 1
Sources & evidence
- ORD record
- ord-8f6a4e2946d146059e0979a130093767
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
Loading…