Ammonium → ethyl 1-[5-bromo-6-oxo-4-[(2,6,6-trimethyl-3-bicyclo[3.1.1]heptanyl)amino]pyridazin-1-yl]cyclobutane-1-carboxylate

HRID 838208Notes

Reaction equation

HRID 838208 reaction equation
[Br:1][c:2]1[c:3](=[O:19])[nH:4][n:5][cH:6][c:7]1[NH:8][CH:9]1[CH:10]([CH3:18])[CH:11]2[C:12]([CH3:16])([CH3:17])[CH:13]([CH2:14]1)[CH2:15]2.[Br:20][C:21]1([C:25](=[O:26])[O:27][CH2:28][CH3:29])[CH2:22][CH2:23][CH2:24]1.[C:30](=[O:31])([O-:32])[O-:33].[CH3:38][N:39]([CH3:40])[CH:41]=[O:42].[Cl-:36].[K+:34].[K+:35].[NH4+:37]>>[Br:1][c:2]1[c:3](=[O:19])[n:4]([C:21]2([C:25](=[O:26])[O:27][CH2:28][CH3:29])[CH2:22][CH2:23][CH2:24]2)[n:5][cH:6][c:7]1[NH:8][CH:9]1[CH:10]([CH3:18])[CH:11]2[C:12]([CH3:16])([CH3:17])[CH:13]([CH2:14]1)[CH2:15]2

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 97595Ethyl 1-bromocyclobutanecarboxylateHCID 178430062HCID 178430062, compound

Product 1

HCID 178470145ethyl 1-[5-bromo-6-oxo-4-[(2,6,6-trimethyl-3-bicyclo[3.1.1]heptanyl)amino]pyridazin-1-yl]cyclobutane-1-carboxylate

Sources & evidence

ORD record
ord-bcda63e3a95248e79a36fcc597c50c38
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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