Ammonium → 1,3-Diamino-4-phenylbutan-2-ol

HRID 838342Notes

Reaction equation

HRID 838342 reaction equation
[BH4-:31].[C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])(=[O:17])[NH:18][CH:19]([CH:20]([CH2:21][NH2:22])[OH:23])[CH2:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[CH3:35][CH2:36][OH:37].[CH:1](=[O:2])[c:3]1[cH:4][cH:5][c:6]([O:7][CH3:8])[cH:9][cH:10]1.[Cl-:33].[NH4+:34].[Na+:32]>>[NH2:18][CH:19]([CH:20]([CH2:21][NH2:22])[OH:23])[CH2:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 702EthanolHCID 923Sodium ionHCID 28123BorohydrideHCID 312444-MethoxybenzaldehydeHCID 11065838tert-butyl N-(4-amino-3-hydroxy-1-phenylbutan-2-yl)carbamate

Product 1

HCID 111377271,3-Diamino-4-phenylbutan-2-ol

Sources & evidence

ORD record
ord-bc40aac5ef0f4fc2bba9e82cf94d679b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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