Hydrochloric Acid → 1-Boc-4-cyano-4-(4-pyridinyl)-piperidine

HRID 838425Notes

Reaction equation

HRID 838425 reaction equation
[C:25](=[O:26])([O-:27])[O-:28].[C:2](#[N:3])[CH2:4][c:5]1[cH:6][cH:7][nH+:8][cH:9][cH:10]1.[CH3:31][S:32]([CH3:33])=[O:34].[CH3:35][CH2:36][O:37][C:38](=[O:39])[CH3:40].[Cl:11][CH2:12][CH2:13][N:14]([C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:22][CH2:23][Cl:24].[ClH:1].[Cs+:29].[Cs+:30]>>[C:2](#[N:3])[C:4]1([c:5]2[cH:6][cH:7][n:8][cH:9][cH:10]2)[CH2:12][CH2:13][N:14]([C:15]([O:16][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:21])[CH2:22][CH2:23]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 679Dimethyl SulfoxideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 11230235N-BOC-N,N-Bis(2-chloroethyl)amineHCID 178510847HCID 178510847, compound

Product 1

HCID 539443251-Boc-4-cyano-4-(4-pyridinyl)-piperidine

Sources & evidence

ORD record
ord-1ada5938dc344a2891bf24773a966483
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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