Dimethylformamide → 6-Chloro-2,4-difluoro-3-trimethylsilylbenzaldehyde

HRID 838665Notes

Reaction equation

[CH2:19]1[O:20][CH2:21][CH2:22][CH2:23]1.[Cl:1][c:2]1[cH:3][c:4]([F:13])[c:5]([Si:9]([CH3:10])([CH3:11])[CH3:12])[c:6]([F:8])[cH:7]1.[O:14]=[CH:15][N:16]([CH3:17])[CH3:18]>>[Cl:1][c:2]1[c:3]([CH:15]=[O:14])[c:4]([F:13])[c:5]([Si:9]([CH3:10])([CH3:11])[CH3:12])[c:6]([F:8])[cH:7]1

Participants

Reactant 3

HCID 6228Dimethylformamide

HCID 8028Tetrahydrofuran

HCID 18935733(4-Chloro-2,6-difluorophenyl)trimethylsilane

Product 1

HCID 866138416-Chloro-2,4-difluoro-3-trimethylsilylbenzaldehyde

Sources & evidence

ORD record: ord-b27b3c482f55473a9d2a64b8883b1f20
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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