Chloride → Tert-butyl 3-[1-hydroxy-5-methoxy-1-(2-phenoxyphenyl)pentyl]piperidine-1-carboxylate

HRID 838760Notes

Reaction equation

HRID 838760 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:14]([c:15]2[c:16]([O:21][c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[cH:17][cH:18][cH:19][cH:20]2)=[O:28])[CH2:11][CH2:12][CH2:13]1.[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:30][O:31][CH2:32][CH2:33][CH2:34][CH2:35][Mg+:36].[Cl-:29]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:14]([c:15]2[c:16]([O:21][c:22]3[cH:23][cH:24][cH:25][cH:26][cH:27]3)[cH:17][cH:18][cH:19][cH:20]2)([OH:28])[CH2:35][CH2:34][CH2:33][CH2:32][O:31][CH3:30])[CH2:11][CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 68825372Tert-butyl 3-(2-phenoxybenzoyl)piperidine-1-carboxylateHCID 178495007HCID 178495007, compound

Product 1

HCID 72283004Tert-butyl 3-[1-hydroxy-5-methoxy-1-(2-phenoxyphenyl)pentyl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-1f471bd6831c47f5824249c0219c806f
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

Loading…