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HRID839208

反应详情

EQUATION

反应方程式

HRID 839208 的结构方程式

REACTANTS

反应物

3
结构：Cl.NO
HCID443297

未命名化合物

结构：CC(=O)[O-].[Na+]
HCID517045

Sodium Acetate

C2H3NaO2

结构：O=Cc1cn(-c2ccccc2)nc1-c1ccc([N+](=O)[O-])o1
HCID20326255

3-(5-Nitrofuran-2-yl)-1-phenyl-1H-pyrazole-4-carbaldehyde

C14H9N3O4

PRODUCTS

生成物

1
结构：O=[N+]([O-])c1ccc(-c2nn(-c3ccccc3)cc2C=NO)o1
HCID54343732

N-{[3-(5-Nitrofuran-2-yl)-1-phenyl-1H-pyrazol-4-yl]methylidene}hydroxylamine

C14H10N4O4

收率 98%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

Add (while stirring) 7.61 g of sodium acetate and 6.58 g of hydroxylamine hydrochloride to 25.0 g of 3-(5-nitro-2-furyl)-1-phenylpyrazole-4-carboxaldehyde in 75 ml of dimethylformamide, the temperature rising slightly. Stir for a further 45 minutes at from 30° to 35° C and for one hour at room temperature. Clafify with degased active charcoal and then pour the solution onto 1 kg of ice and water. Vacuum filter and wash with water to obtain 98% yield of 3-(5-nitro-2-furyl)-1-phenylpyrazole-4-carboxaldehydeoxime [m.p. 199° to 201° C with decomposition (from toluene)].

WORKUP

后处理

  1. customClafify with degased active charcoal
  2. additionpour the solution onto 1 kg of ice and water
  3. filtrationVacuum filter
  4. washwash with water