huagongshe.com
HRID839452

反应详情

EQUATION

反应方程式

HRID 839452 的结构方程式

REACTANTS

反应物

4
结构：CS(C)=O
HCID679

Dimethyl sulfoxide

C2H6OS

结构：O=C1c2ccccc2C(=O)N1O
HCID10665

1H-Isoindole-1,3(2H)-dione, 2-hydroxy-

C8H5NO3

结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：CC(C)(C)OC(=O)C(Br)c1ccccc1
HCID11000147

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(C)OC(=O)C(ON1C(=O)c2ccccc2C1=O)c1ccccc1
HCID20249493

未命名化合物

收率 78%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

(a)(i) A mixture of N-hydroxyphthalimide (24.5g), anhydrous potassium carbonate (16.5g), t-butyl α-bromophenylacetate (41g) and dimethylsulphoxide (225 ml) was stirred for 18 hours and was then poured into water (1.2 liters). The precipitated solid was filtered off, washed well with water, dried, and crystallised from industrial methylated spirits to give N-[α-(t-butoxycarbonyl) benzyloxy] phthalimide (41g, 78%); m.p. 120.6°-121.5°.

WORKUP

后处理

  1. filtrationThe precipitated solid was filtered off
  2. washwashed well with water
  3. customdried
  4. customcrystallised from industrial methylated spirits