Methyl Salicylate → HCID 54403786, compound

HRID 839486Notes

Reaction equation

HRID 839486 reaction equation
[C:1]([O:10]C)(=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:12]1[O:15][CH:13]1[CH3:14].[CH2:16](N(CC)CC)C>>[CH3:14][CH:13]1[C:12](=[O:15])[C:1](=[O:10])[C:2]2[CH:8]=[CH:7][CH:6]=[CH:5][C:3]=2[O:4][CH2:16]1

Participants

4

Reactant 3

HCID 4133Methyl SalicylateHCID 6378Propylene OxideHCID 8471Triethylamine

Product 1

HCID 54403786HCID 54403786, compound

Conditions

Temperature
120 °C

Procedure

To a one liter, stainless steel autoclave was added 535 g. (3.52) of methyl salicylate (III) and 6.0 g. triethylamine. The resulting mixture was heated at 120° C, while 260 g. (4.5 moles) of propylene oxide was added over a one hour period. The reaction mixture was then heated up to 150° C and allowed to digest for 8 hr.

Workup

  1. temperatureThe reaction mixture was then heated up to 150° C

Sources & evidence

ORD record
ord-0adc63da5b0f4faab28b598680202019
Source dataset
uspto-grants-1978_06
Patent number
US04096119

Reaction notes

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