Phenylhydrazine → 2-phenylphthalazin-1(2h)-one

HRID 839500Notes

Reaction equation

HRID 839500 reaction equation
Br[CH:2](Br)[C:3]1[C:4]([C:9]([OH:11])=O)=[CH:5][CH:6]=[CH:7][CH:8]=1.[C:13]1([NH:19][NH2:20])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[C:13]1([N:19]2[N:20]=[CH:2][C:3]3[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=3)[C:9]2=[O:11])[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 7516PhenylhydrazineHCID 3455532-(dibromomethyl)benzoic acid

Product 1

HCID 2356262-phenylphthalazin-1(2h)-oneYield 30.1%

Procedure

α,α-dibromo-o-toluic acid (29.4 g) and phenylhydrazine (34.6 g) were allowed to react as in Example 4. There was obtaoined 6.7 g (yield: 30%) of 2-phenyl-1-phthalazinone having a melting poin of 104°-105° C.

Sources & evidence

ORD record
ord-08dba768ac024693b221cbd8dfac69ec
Source dataset
uspto-grants-1978_06
Patent number
US04096143

Reaction notes

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