反应详情

温度

80 °C

A mixture of 100 mmol of benzaldehyde, 100 mmol of sodium cyanide and 50 ml of N,N-dimethylformamide was stirred at a temperature of 80° C for 30 min. Then, an amount of 100 mmol of 2-chloro-3,3,4,4-tetramethylcyclobutanone was added over a period of 30 min and stiring was continued for six hours. At the end of this period the reactants were fully converted and alpha-cyanobenzyl 2,2,3,3-tetramethylcyclopropanecarboxylate was obtained in a yield of 65%.

1. waitstiring was continued for six hours