Benzene → HCID 20322125, compound

HRID 839830Notes

Reaction equation

HRID 839830 reaction equation
C([O:3][C:4](=[O:18])[CH:5]([CH2:11][CH2:12][CH:13]([CH3:17])[CH2:14][CH2:15][Br:16])C(OCC)=O)C.Br.C1C=CC=CC=1>O>[Br:16][CH2:15][CH2:14][CH:13]([CH3:17])[CH2:12][CH2:11][CH2:5][C:4]([OH:18])=[O:3]

Participants

5

Reactant 3

HCID 241BenzeneHCID 260Hydrogen Bromide2×HCID 54445285HCID 54445285, compound

Product 1

HCID 20322125HCID 20322125, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

30 g of (5-bromo-3-methylpentyl)-malonic acid diethyl ester were heated to the boil, while stirring, with 15 ml of 48% HBr and 15 ml of HBr/glacial acetic acid, whereby the low-boiling products were distilled off. After 7 hours the cooled reaction solution was distributed between benzene and water and the organic phase was evaporated with MgSO4 after drying and distilled off.

Workup

  1. distillationwere distilled off
  2. customAfter 7 hours the cooled reaction solution
  3. customthe organic phase was evaporated with MgSO4
  4. customafter drying
  5. distillationdistilled off

Sources & evidence

ORD record
ord-caacd8eb435b4ee38d7d1ac4416721cf
Source dataset
uspto-grants-1978_06
Patent number
US04097496

Reaction notes

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