Methyl Acetate → Methyl 6-methoxymethyloxy-2-naphthyl-alpha-methylacetate

HRID 840031Notes

Reaction equation

HRID 840031 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([CH:12]([CH3:17])[C:13]([O:15][CH3:16])=[O:14])[CH:6]=[CH:5]2.[CH3:18][O:19][C:20](=O)C.COCCl>CN(C)C=O>[CH3:18][O:19][CH2:20][O:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[CH:8]=[C:7]([CH:12]([CH3:17])[C:13]([O:15][CH3:16])=[O:14])[CH:6]=[CH:5]2

Participants

5

Reactant 3

HCID 6584Methyl AcetateHCID 7864Chloromethyl Methyl EtherHCID 5988972-(6-Hydroxy-naphthalen-2-yl)-propionic acid methyl ester

Product 1

HCID 21412543Methyl 6-methoxymethyloxy-2-naphthyl-alpha-methylacetate

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A mixture of 23 g. of methyl 6-hydroxy-2naphthyl-α-methylacetate, methylacetate, 25 g. of chlorodimethyl ether, and 500 ml. of dimethylformamide is allowed to stand at room temperature for 12 hours. The reaction mixture is evaporated under reduced pressure to give methyl 6-methoxymethyloxy-2-naphthyl-α-methylacetate.

Workup

  1. additionA mixture of 23 g
  2. customThe reaction mixture is evaporated under reduced pressure

Sources & evidence

ORD record
ord-cdff7ea19b474a98af5a7569e8abaf65
Source dataset
uspto-grants-1978_06
Patent number
US04097674

Reaction notes

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