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HRID840197

反应详情

EQUATION

反应方程式

HRID 840197 的结构方程式

REACTANTS

反应物

2
结构：CCOC(C)=O
HCID8857

Ethyl acetate

C4H8O2

结构：O=[N+]([O-])c1ccc2c(c1)CS(=O)(=O)N2CCF
HCID22622762

未命名化合物

PRODUCTS

生成物

1
结构：Nc1ccc2c(c1)CS(=O)(=O)N2CCF
HCID22622761

未命名化合物

收率 99.5%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：[Pd]
溶剂HCID23938

Palladium

Pd

PROCEDURE

实验过程

The product of Step 1 (1.25 g, 4.8 mmol) is dissolved into EtOAc (30 mL) in a Parr bottle and 10% Pd/C (100 mg) added under nitrogen. The mixture is hydrogenated on a Parr apparatus for 4 hrs at 40 psi. Filtration and evaporation of solvent gave a solid (1.1 g, 99%). Mp 119-21° C. HRMS (FAB) calcd for C9H11FN2O2S +H1 231.0603, found 231.0610.

WORKUP

后处理

  1. additionadded under nitrogen
  2. filtrationFiltration and evaporation of solvent