Hydrochloric Acid → HCID 22618723, compound

HRID 842299Notes

Reaction equation

HRID 842299 reaction equation
C(OC([NH:8][C:9]([CH2:31][CH3:32])([CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[CH:16][CH:15]=1)[CH2:10][OH:11])=O)(C)(C)C.[ClH:33]>O1CCCC1.O1CCOCC1>[ClH:33].[NH2:8][C:9]([CH2:31][CH3:32])([CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][C:17]([O:20][CH2:21][CH2:22][CH2:23][CH2:24][C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)=[CH:16][CH:15]=1)[CH2:10][OH:11]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 22618896HCID 22618896, compound

Product 1

HCID 22618723HCID 22618723, compound

Reagents, catalysts & solvents 2

HCID 8028TetrahydrofuranSolventHCID 312751,4-DioxaneSolvent

Procedure

To a solution of 2-tert-butoxycarbonylamino-2-ethyl-4-(4-(4-phenylbutyloxy)phenyl)butanol (3.2 g) in tetrahydrofuran (10 ml) was added a solution of 4M hydrochloric acid in dioxane (10 ml) and the mixture was stirred for 3 hours. The solvent was distilled away to give the subject compound (3 g).

Workup

  1. distillationThe solvent was distilled away

Sources & evidence

ORD record
ord-32e01a67b7894ec997d1342ed21bd5db
Source dataset
uspto-grants-2002_04
Patent number
US06372800B1

Reaction notes

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