Iodine → HCID 11323077, compound

HRID 842438Notes

Reaction equation

HRID 842438 reaction equation
[C:1]1([CH2:7][C@@H]2COC(=O)N2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[I:14]I.[C:16]([O-:19])(O)=[O:17].[Na+]>C(Cl)Cl>[I:14][C@@H:3]1[C@@H:4]2[CH2:5][C@@H:6]([C:16](=[O:17])[O:19]2)[C@H:1]([CH3:7])[CH2:2]1

Participants

5

Reactant 3

HCID 807IodineHCID 516892Sodium BicarbonateHCID 2734969(R)-4-Benzyl-2-oxazolidinone

Product 1

HCID 11323077HCID 11323077, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

reacting said (1R,6R)-6-methyl-3-cyclohexene-1-carboxylic acid (5) with I2, KI and NaHCO3 in methylene chloride to produce (1R,2R,4S,5s)4-iodo-2-methyl-6-oxabicyclo[3.2.1]octan-7-one (8),

Sources & evidence

ORD record
ord-f0992252fc17439da4585191e6a1b795
Source dataset
uspto-grants-2002_04
Patent number
US06375943B1

Reaction notes

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