反应详情

DIEA (60 μL, 0.35 mmol) is added to a mixture of SC-PEG 40 kDa (4, 1.0 g, 0.025 mmol) and 1 (0.15 g, 0.5 mmol) in DCM (10 mL) and DMF (10 mL) and the mixture is stirred overnight at room temperature. The solvent is removed in vacuo and the residue is recrystallized from IPA to give PEG-carbamate-Ara-C (5).

1. customThe solvent is removed in vacuo
2. customthe residue is recrystallized from IPA