Diethyl Oxalate → HCID 9861952, compound

HRID 844357Notes

Reaction equation

HRID 844357 reaction equation
[CH:1]1([C:11]2[CH:12]=[C:13]([C:17](=[O:19])[CH3:18])[CH:14]=[CH:15][CH:16]=2)[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][CH2:2]1.[C:20](OCC)(=[O:26])[C:21]([O:23]CC)=[O:22].[O-]CC.[Na+]>>[O:26]=[C:20]([CH2:18][C:17](=[O:19])[C:13]1[CH:14]=[CH:15][CH:16]=[C:11]([CH:1]2[C:10]3[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=3)[CH2:4][CH2:3][CH2:2]2)[CH:12]=1)[C:21]([OH:23])=[O:22]

Participants

4

Reactant 3

HCID 7268Diethyl OxalateHCID 2723922Sodium ethoxideHCID 22613226HCID 22613226, compound

Product 1

HCID 9861952HCID 9861952, compound

Procedure

Isomer B: As described above, 0.048 g (0.19 mmol) of 1-[3-(1,2,3,4-tetrahydronaphthalen-1-yl)-phenyl]-ethanone (isomer B), 0.056 g (0.38 mmol) diethyl oxalate, and 0.026 g (0.38 mmol) sodium ethoxide were reacted to give the title compound which was used without further purification.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-0468f40d8041482f9509827bedf70fe2
Source dataset
uspto-grants-2002_04
Patent number
US06380249B1

Reaction notes

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