Hydrochloric Acid → 2-benzoylhydrazinecarboxamide

HRID 844403Notes

Reaction equation

HRID 844403 reaction equation
Cl.[C:2]([NH:10][NH2:11])(=[O:9])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[O-:12][C:13]#[N:14].[K+]>O>[C:2]([NH:10][NH:11][C:13]([NH2:14])=[O:12])(=[O:9])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 11955BenzoylhydrazineHCID 11378442Potassium cyanate

Product 1

HCID 2304692-benzoylhydrazinecarboxamide

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A four neck flask (1000 ml) equipped with a thermometer and a stirrer was charged with 78.2 g (0.75 mol) of 35% hydrochloric acid and 700 ml of deionized water. Added thereto was 68.0 g (0.5 mol) of benzohydrazide at room temperature (20° C.) while stirring, and then 60.7 g (0.75 mol) of potassium cyanate was gradually added in 30 minutes. Stirring was continued at 30° C. for one hour, and then crystal was filtered off and washed with 200 ml of deionized water. This was dried under reduced pressure to obtain white crystal.

Workup

  1. customA four neck flask (1000 ml) equipped with a thermometer and a stirrer
  2. additionAdded
  3. customat room temperature
  4. custom(20° C.)
  5. stirringStirring
  6. filtrationcrystal was filtered off
  7. washwashed with 200 ml of deionized water
  8. customThis was dried under reduced pressure
  9. customto obtain white crystal

Sources & evidence

ORD record
ord-21bb59e1c4d7452bb98c71e5ea6442d5
Source dataset
uspto-grants-2002_04
Patent number
US06380288B1

Reaction notes

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