Furfural → HCID 5098031, compound

HRID 844406Notes

Reaction equation

HRID 844406 reaction equation
[C:1]1([S:7]([NH:10][NH2:11])(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH:12](=O)[C:13]1[O:17][CH:16]=[CH:15][CH:14]=1>CO>[O:17]1[CH:16]=[CH:15][CH:14]=[C:13]1[CH:12]=[N:11][NH:10][S:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)(=[O:8])=[O:9]

Participants

4

Reactant 2

HCID 7362FurfuralHCID 65723Benzenesulfonyl hydrazide

Product 1

HCID 5098031HCID 5098031, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A four neck flask (1 liter) equipped with a thermometer, a reflux condenser and a stirrer was charged with 86 g (0.5 mol) of benzenesulfonohydrazide and 700 ml of methanol, and 57.6 g (0.6 mol) of furfural was dropwise added thereto in one hour while stirring at room temperature and heated under reflux for about 5 hours. The reaction liquid was cooled down to 20° C. or lower, and then crystal was filtered off and dried under reduced pressure, whereby white crystal was obtained.

Workup

  1. customA four neck flask (1 liter) equipped with a thermometer, a reflux condenser and a stirrer
  2. additionwas dropwise added
  3. temperatureheated
  4. temperatureunder reflux for about 5 hours
  5. customThe reaction liquid
  6. temperaturewas cooled down to 20° C.
  7. filtrationlower, and then crystal was filtered off
  8. customdried under reduced pressure, whereby white crystal
  9. customwas obtained

Sources & evidence

ORD record
ord-de48062296274ee0a193c82752e6dbc1
Source dataset
uspto-grants-2002_04
Patent number
US06380288B1

Reaction notes

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