2-Cyclohexen-1-one, 4,4-dimethyl- → Cyclohexanone, 4,4-dimethyl-

HRID 844424Notes

Reaction equation

HRID 844424 reaction equation
[CH3:1][C:2]1([CH3:9])[CH2:7][CH2:6][C:5](=[O:8])[CH:4]=[CH:3]1.[H][H]>[Pd].CCOC(C)=O>[CH3:1][C:2]1([CH3:9])[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1

Participants

5

Reactant 2

HCID 1368392-Cyclohexen-1-one, 4,4-dimethyl-HCID 178418361HCID 178418361, compound

Product 1

HCID 138166Cyclohexanone, 4,4-dimethyl-Yield 92.5%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

6.7 g of 4,4-dimethyl-2-cyclohexen-1-one and 2 g of 10% Pd/C are added to 65 ml of EtOAc and the mixture is hydrogenated at RT under atmospheric pressure until the theoretical volume of hydrogen has been absorbed. The catalyst is filtered off and the filtrate is then concentrated to give 6.3 g of the expected product.

Workup

  1. customhas been absorbed
  2. filtrationThe catalyst is filtered off
  3. concentrationthe filtrate is then concentrated

Sources & evidence

ORD record
ord-39b1a2aaa52348eaa50e809193d2df41
Source dataset
uspto-grants-2002_04
Patent number
US06380230B1

Reaction notes

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