Ammonia → L-Phenylalanine

HRID 845012Notes

Reaction equation

HRID 845012 reaction equation
[C:1]([OH:11])(=[O:10])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[NH3:12]>>[NH2:12][C@H:2]([C:1]([OH:11])=[O:10])[CH2:3][C:4]1[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=1

Participants

3

Reactant 2

HCID 222AmmoniaHCID 87842-Propenoic acid, 3-phenyl-

Product 1

HCID 6140L-Phenylalanine

Procedure

Phenylalanine can be produced by adding cinnamic acid and an ammonia generator to the culture medium during cultivation. Alternatively, phenylalanine may be produced by dissolving or suspending the microbial cells (live or treated cells) in an aqueous medium containing cinnamic acid and an ammonia generator and allowing the solution or suspension to stand (with stirring when desired) while maintaining the temperature at a suitable level between 10° and 70° C.

Sources & evidence

ORD record
ord-4d582c864c1447b78ddc08befb202206
Source dataset
uspto-grants-1988_07
Patent number
US04755466

Reaction notes

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