Piperidine → HCID 13417342, compound

HRID 845073Notes

Reaction equation

HRID 845073 reaction equation
[C:1]([NH:9][C:10]1[CH:15]=[C:14]([CH2:16]N2CCCC2)[C:13]([OH:22])=[C:12]([CH2:23][N:24]2[CH2:28][CH2:27][CH2:26][CH2:25]2)[CH:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH:29]1[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]1.N1CCC[CH2:36]1>>[C:1]([NH:9][C:10]1[CH:15]=[C:14]([CH2:16][N:29]2[CH2:34][CH2:33][CH2:32][CH2:31][CH2:30]2)[C:13]([OH:22])=[C:12]([CH2:23][N:24]2[CH2:25][CH2:26][CH2:27][CH2:28][CH2:36]2)[CH:11]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 3

HCID 8082PiperidineHCID 31268PyrrolidineHCID 10339688HCID 10339688, compound

Product 1

HCID 13417342HCID 13417342, compound

Procedure

This example describes the synthesis of a compound having the formula ##STR157## This compound was prepared as was the compound of Example III with the exception that piperidine was substituted for pyrrolidine yielding white crystals: mp 138°-140° C. The IR and spectra were consistent with the assigned structure and the elemental analysis was consistent with the empirical formula (C25H33N3O2.2HCl.2H2O).

Workup

  1. customthe synthesis of a compound
  2. customwas prepared

Sources & evidence

ORD record
ord-aa0143590eb34b29afc20da28e712a8b
Source dataset
uspto-grants-1988_07
Patent number
US04755527

Reaction notes

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