Oxalyl chloride → HCID 20133512, compound

HRID 845093Notes

Reaction equation

HRID 845093 reaction equation
[C:1](Cl)(=O)C(Cl)=O.[CH3:7][C:8]([C:11]1[CH:12]=[C:13]([S:22][CH2:23][CH:24]([OH:31])[CH2:25][S:26][CH2:27][C:28]([OH:30])=[O:29])[CH:14]=[C:15]([C:18]([CH3:21])([CH3:20])[CH3:19])[C:16]=1[OH:17])([CH3:10])[CH3:9]>C1C=CC=CC=1>[CH3:1][O:29][C:28](=[O:30])[CH2:27][S:26][CH2:25][CH:24]([OH:31])[CH2:23][S:22][C:13]1[CH:12]=[C:11]([C:8]([CH3:7])([CH3:9])[CH3:10])[C:16]([OH:17])=[C:15]([C:18]([CH3:19])([CH3:20])[CH3:21])[CH:14]=1

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 20133523HCID 20133523, compound

Product 1

HCID 20133512HCID 20133512, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Oxalyl chloride (3 ml) was added to a solution of the compound of Example 41 (2.3 g) in benzene (50 ml) and stirred for 3 hours at room temperature. The reaction volume was reduced and methyl alcohol (100 ml) added. After evaporation of the solvents, the product (an oil) was purified by chromatography on silica.

Workup

  1. additionadded
  2. customAfter evaporation of the solvents
  3. customthe product (an oil) was purified by chromatography on silica

Sources & evidence

ORD record
ord-5c82a2630ccd4c38b5443081cf763bbb
Source dataset
uspto-grants-1988_07
Patent number
US04755524

Reaction notes

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