Potassium Carbonate → HCID 70407125, compound

HRID 845240Notes

Reaction equation

HRID 845240 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[N:7]=[CH:8][C:9]2[N:10](C(=O)C)[C:11]3[C:16]([C:17]=2[CH:18]=1)=[C:15]([CH2:19][C:20]1[NH:21][CH:22]=[CH:23][N:24]=1)[CH:14]=[CH:13][CH:12]=3)=[O:5])[CH3:2].C([O-])([O-])=O.[K+].[K+]>C(O)C>[CH2:1]([O:3][C:4]([C:6]1[N:7]=[CH:8][C:9]2[NH:10][C:11]3[C:16]([C:17]=2[CH:18]=1)=[C:15]([CH2:19][C:20]1[NH:24][CH:23]=[CH:22][N:21]=1)[CH:14]=[CH:13][CH:12]=3)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 70407076HCID 70407076, compound

Product 1

HCID 70407125HCID 70407125, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A suspension of 0.11 g of 9-acetyl-5-(1-imidazolylmethyl)-beta-carboline-3-carboxylic acid ethyl ester in 5 ml of ethanol is mixed with 10 mg of K2CO3 and refluxed for two hours. After filtering, the solution is concentrated in a vacuum, the residue is mixed with water, suctioned off and recrystallized from water. Yield 70 mg (71%).

Workup

  1. temperaturerefluxed for two hours
  2. filtrationAfter filtering
  3. concentrationthe solution is concentrated in a vacuum
  4. additionthe residue is mixed with water
  5. customrecrystallized from water

Sources & evidence

ORD record
ord-02ec03d702b54b4892f0322210ae0531
Source dataset
uspto-grants-1988_07
Patent number
US04757070

Reaction notes

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