Diethylhydroxylamine → 3-[(Diethylamino)oxy]-N-(2,4,4-trimethylpentan-2-YL)propanamide

HRID 845885Notes

Reaction equation

HRID 845885 reaction equation
[CH2:1]([N:3]([CH2:5][CH3:6])[OH:4])[CH3:2].CC(C)([O-])C.[K+].[C:13]([NH:21][C:22](=[O:25])[CH:23]=[CH2:24])([CH2:16][C:17]([CH3:20])([CH3:19])[CH3:18])([CH3:15])[CH3:14]>O1CCCC1>[C:13]([NH:21][C:22](=[O:25])[CH2:23][CH2:24][O:4][N:3]([CH2:5][CH3:6])[CH2:1][CH3:2])([CH2:16][C:17]([CH3:18])([CH3:19])[CH3:20])([CH3:14])[CH3:15]

Participants

5

Reactant 3

HCID 19463DiethylhydroxylamineHCID 171970N-tert-OctylacrylamideHCID 23665647Potassium tert-butoxide

Product 1

HCID 569757343-[(Diethylamino)oxy]-N-(2,4,4-trimethylpentan-2-YL)propanamide

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The procedure of Example I is repeated using diethylhydroxylamine, potassium-tert-butoxide and N-tert-octylacrylamide in tetrahydrofuran to afford the title compound.

Sources & evidence

ORD record
ord-cdb9ab96903a48a0bdd62cc91fed0ab7
Source dataset
uspto-grants-1988_07
Patent number
US04760179

Reaction notes

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