Hydrochloric Acid → HCID 13922800, compound

HRID 846216Notes

Reaction equation

HRID 846216 reaction equation
[Na].CN(C)C([S:6][C:7]1[CH:12]=[CH:11][C:10]([C:13](=[O:20])[CH2:14][CH2:15][C:16]([O:18][CH3:19])=[O:17])=[CH:9][CH:8]=1)=O.O.Cl>CO>[SH:6][C:7]1[CH:8]=[CH:9][C:10]([C:13](=[O:20])[CH2:14][CH2:15][C:16]([O:18][CH3:19])=[O:17])=[CH:11][CH:12]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 5360545SodiumHCID 14211171HCID 14211171, compound

Product 1

HCID 13922800HCID 13922800, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Sodium 280 mg, was dissolved in anhydrous methanol, 50 ml, under an N2 atmosphere. To the resulting solution there was added 5.0 g of the compound from Step D. The mixture was stirred at room temperature overnight, then poured into a mixture containing 30 ml of water and 7 ml of concentrated HCl. The resulting yellow solid was collected by filtration, washed with water and dried in air to give the title compound, mp 83°-84°.

Workup

  1. additionpoured into a mixture
  2. filtrationThe resulting yellow solid was collected by filtration
  3. washwashed with water
  4. customdried in air

Sources & evidence

ORD record
ord-68b77e63e9a14c2d839bbd9e901e566e
Source dataset
uspto-grants-1992_08
Patent number
US05135940

Reaction notes

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