Methanol → HCID 13693406, compound

HRID 846236Notes

Reaction equation

HRID 846236 reaction equation
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([C:9](=[O:17])[CH:10]([CH3:16])[CH2:11][C:12]([O:14]C)=[O:13])=[CH:5][CH:4]=1.[OH-].[Na+].CO>C1COCC1>[CH3:1][S:2][C:3]1[CH:4]=[CH:5][C:6]([C:9](=[O:17])[CH:10]([CH3:16])[CH2:11][C:12]([OH:14])=[O:13])=[CH:7][CH:8]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 14798Sodium HydroxideHCID 13693403HCID 13693403, compound

Product 1

HCID 13693406HCID 13693406, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The ester from Step B (1.07 g) was saponified with 1N NaOH (5 ml) and methanol (5 ml) and THF (5 ml) to provide after acidification, extraction into CH and evaporation to dryness the title compound, mp 69°-71° C.

Workup

  1. customto provide
  2. extractionafter acidification, extraction
  3. custominto CH and evaporation to dryness the title compound, mp 69°-71° C.

Sources & evidence

ORD record
ord-6efb5349747849ec9cd47f01c1840f87
Source dataset
uspto-grants-1992_08
Patent number
US05135940

Reaction notes

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