Diphosgene → HCID 19882834, compound

HRID 846498Notes

Reaction equation

HRID 846498 reaction equation
[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[C:6]([CH3:10])=[CH:5][C:3]=1[NH2:4].Cl[C:12](OC(Cl)(Cl)Cl)=[O:13]>C1(C)C=CC=CC=1>[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[C:6]([CH3:10])=[CH:5][C:3]=1[N:4]=[C:12]=[O:13]

Participants

4

Reactant 2

HCID 10426DiphosgeneHCID 2833142,4-Dichloro-5-methylaniline

Product 1

HCID 19882834HCID 19882834, compoundYield 107.9%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

In a manner similar to Kurita, et al., J. Org. Chem., 41, 2070 (1976), incorporated herein by reference, the reaction of 3.43 g (0.0156 mole) of 2,4-dichloro-5-methylaniline and 3.5 g (0.018 mole) of trichloromethyl chloroformate in 50 mL of toluene produced 3.4 g of 2,4-dichloro-5-methylphenyl isocyanate.

Sources & evidence

ORD record
ord-91b1f67804804a0f8d454bc9684c7386
Source dataset
uspto-grants-1992_08
Patent number
US05136868

Reaction notes

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