Diethylamine → 1-[4-(Diethylamino)-2-butynyl]-1,3-dihydro-3-methyl-2H-imidazol-2-one

HRID 846651Notes

Reaction equation

[CH3:1][N:2]1[CH2:6][CH2:5][N:4]([CH2:7][C:8]#[CH:9])[C:3]1=[O:10].[CH2:11]([NH:13][CH2:14][CH3:15])[CH3:12].N1CCC[CH2:17]1>>[CH2:11]([N:13]([CH2:14][CH3:15])[CH2:17][C:9]#[C:8][CH2:7][N:4]1[CH:5]=[CH:6][N:2]([CH3:1])[C:3]1=[O:10])[CH3:12]

Participants

Reactant 3

HCID 8021Diethylamine

HCID 31268Pyrrolidine

HCID 113555131-Methyl-3-(2-propynyl)-2-imidazolidinone

Product 1

HCID 150655321-[4-(Diethylamino)-2-butynyl]-1,3-dihydro-3-methyl-2H-imidazol-2-one

Procedure

This product, a liquid, was prepared according to Example 1, Part B by substituting 1,3-dihydro-1-methyl-3-(2-propynyl)-2H-imidazol-2-one for 1-methyl-3-(2-propynyl)-2-imidazolidinone and diethylamine for pyrrolidine.

Workup

customThis product, a liquid, was prepared

Sources & evidence

ORD record: ord-bf8add972fd5405c9fbd23bcb154b204
Source dataset: uspto-grants-1992_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05137905

Reaction notes

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