Iodoethane → HCID 19883213, compound

HRID 846820Notes

Reaction equation

HRID 846820 reaction equation
Cl.[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:10]3[CH2:21][NH:20][CH2:19][CH2:18][C:11]=3[N:12]=[C:13]([NH:15][CH2:16][CH3:17])[N:14]=2)=[CH:5][CH:4]=1.I[CH2:23][CH3:24]>>[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:10]3[CH2:21][N:20]([CH2:23][CH3:24])[CH2:19][CH2:18][C:11]=3[N:12]=[C:13]([NH:15][CH2:16][CH3:17])[N:14]=2)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 19883233HCID 19883233, compound

Product 1

HCID 19883213HCID 19883213, compoundYield 100%

Procedure

The title compound was prepared as described in Example 9 starting with 4-(4-chlorophenyl)-2-ethylamino-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine hydrochloride (3.0 g, 9.3 mmol) and iodoethane (0.74 mL, 18.5 mmol) to produce 2.9 g (100%) of 4-(4-chlorophenyl)-6-ethyl-2- ethylamino-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine. m.p. 129°-132° C. MS: 317 (MH+).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-eff34aae77d14565875e89f29dcc90dd
Source dataset
uspto-grants-1992_08
Patent number
US05137890

Reaction notes

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