Sodium Acetate → 2,4-Bis-(acetoxymethyl)-1,5-diisopropylbenzene

HRID 846878Notes

Reaction equation

HRID 846878 reaction equation
Cl[CH2:2][C:3]1[CH:8]=[C:7]([CH2:9]Cl)[C:6]([CH:11]([CH3:13])[CH3:12])=[CH:5][C:4]=1[CH:14]([CH3:16])[CH3:15].[C:17]([O-:20])(=[O:19])[CH3:18].[Na+]>CN(C)C=O>[C:17]([O:20][CH2:2][C:3]1[CH:8]=[C:7]([CH2:9][O:20][C:17](=[O:19])[CH3:18])[C:6]([CH:11]([CH3:13])[CH3:12])=[CH:5][C:4]=1[CH:14]([CH3:16])[CH3:15])(=[O:19])[CH3:18]

Participants

4

Reactant 2

HCID 517045Sodium AcetateHCID 148505431,5-Bis(chloromethyl)-2,4-di(propan-2-yl)benzene

Product 1

HCID 148505442,4-Bis-(acetoxymethyl)-1,5-diisopropylbenzene

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

40.0 g (154 mmol) of the compound from Example 1 and 22.7 g (277 mmol) of sodium acetate are heated overnight at 80° C. in 200 ml of dimethylformamide. After distilling off the solvent, the residue is taken up with petroleum ether, washed with water and dried using sodium sulphate.

Workup

  1. distillationAfter distilling off the solvent
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-09ea600d566a4422a9581aac17eb5544
Source dataset
uspto-grants-1992_08
Patent number
US05138090

Reaction notes

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