Phthalimide → 3-Hexadecylthio-2-methoxymethylpropylamine

HRID 846997Notes

Reaction equation

HRID 846997 reaction equation
[C:1]([O:5][C:6](NC(COC(=O)NCCCCCCCCCCCCCCCCCC)CN)=O)(C)(C)C.ClCCCS([NH:42][CH2:43][CH:44](OC)[CH2:45][S:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH3:62])(=O)=O.C1(=O)NC(=O)C2=CC=CC=C12>>[CH2:47]([S:46][CH2:45][CH:44]([CH2:1][O:5][CH3:6])[CH2:43][NH2:42])[CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH2:53][CH2:54][CH2:55][CH2:56][CH2:57][CH2:58][CH2:59][CH2:60][CH2:61][CH3:62]

Participants

4

Reactant 3

HCID 6809PhthalimideHCID 148350012-tert-Butoxycarbonylamino-3-octadecylcarbamoyloxypropylamineHCID 14835022HCID 14835022, compound

Product 1

HCID 148350103-Hexadecylthio-2-methoxymethylpropylamine

Procedure

3-Hexadecylthio-2-methoxymethylpropanol IV k3 is allowed to react and worked up by the same procedure as described in (4). The phthalimide compound m.p. 45° C. The summary of the experimental condition and the physical data of the product are listed in Tables 5 and 6.

Workup

  1. customto react

Sources & evidence

ORD record
ord-00fc6b7483624b9c82ed8f7bc6db8255
Source dataset
uspto-grants-1992_08
Patent number
US05138067

Reaction notes

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