HRID847019

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID88163

Lithium azide

LiN3

结构：CCCCCCCCCCCCCCCCSCC(CN=[N+]=[N-])NC(=O)OC(C)(C)C

HCID14835095

未命名化合物

结构：CCCCCCCCCCCCCCCCSCC(COS(C)(=O)=O)CC(C)OC(=O)c1ccccc1

HCID53635267

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCSCC(CN=[N+]=[N-])CC(C)OC(=O)c1ccccc1

HCID19884195

未命名化合物

收率 96.6%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

A mixture of the previously obtained 2-(2-benzoyloxypropan-1-yl)-3-n-hexadecylthiopropyl methanesulfonate m12a and 1.297 g (26.5 mM) of lithium azide in 50 ml of dimethylformamide is allowed to react by the same procedure as described in (53) and 1.291 g (96.6% yield) of the titled compound m12b is obtained.

WORKUP

后处理

customto react by the same procedure

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2830154dfc284b2190328ccf55019e08
来源数据集: uspto-grants-1992_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05138067
来源说明: uspto-grants-1992_08

反应 SMILES

CS(O[CH2:6][CH:7]([CH2:26][CH:27]([O:29][C:30](=[O:37])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)[CH3:28])[CH2:8][S:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])(=O)=O.[N-:38]=[N+:39]=[N-:40].[Li+].N(CC(NC(OC(C)(C)C)=O)CSCCCCCCCCCCCCCCCC)=[N+]=[N-]>CN(C)C=O>[N:38]([CH2:6][CH:7]([CH2:26][CH:27]([O:29][C:30](=[O:37])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)[CH3:28])[CH2:8][S:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])=[N+:39]=[N-:40]