Hydrochloric Acid → HCID 11321766, compound

HRID 847193Notes

Reaction equation

HRID 847193 reaction equation
F[C:2]1[CH:22]=[CH:21][C:5]2[O:6][C:7]3[CH:20]=[CH:19][CH:18]=[CH:17][C:8]=3[CH:9]=[C:10]([O:11]CCN(C)C)[C:4]=2[CH:3]=1.Cl>>[O:11]=[C:10]1[C:4]2[CH:3]=[CH:2][CH:22]=[CH:21][C:5]=2[O:6][C:7]2[CH:20]=[CH:19][CH:18]=[CH:17][C:8]=2[CH2:9]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 197605192-Fluoro-11-[beta-(dimethylamino) ethoxy]dibenz[b,f]oxepin

Product 1

HCID 11321766HCID 11321766, compound

Procedure

Reflux of 25 ml of 2-fluoro-11-[β-(dimethylamino)-ethoxy]dibenz[b,f]oxepin stock solution produced no apparent decomposition after 45 minutes. Addition of 2.5 ml of concentrated hydrochloric acid and further reflux for 10 mins gave complete decomposition to 10,11-dihydro-10-oxodibenz[b,f]oxepin.

Workup

  1. customproduced no apparent decomposition after 45 minutes
  2. temperaturefurther reflux for 10 mins

Sources & evidence

ORD record
ord-33922ff8400349039e373c01f6de26c7
Source dataset
uspto-grants-1992_08
Patent number
US05140027

Reaction notes

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