Hydrogen Peroxide → HCID 19881056, compound

HRID 847389Notes

Reaction equation

HRID 847389 reaction equation
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[C:12](=[O:13])[C:11]2[CH:14]=[CH:15][S:16][C:10]=2S[CH2:8][CH2:7]1.OO.[S:19]([O-:22])(O)=[O:20].[Na+]>C(O)=O>[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][N:6]1[C:12](=[O:13])[C:11]2[CH:14]=[CH:15][S:16][C:10]=2[S:19](=[O:22])(=[O:20])[CH2:8][CH2:7]1

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 19881109HCID 19881109, compoundHCID 23665763Sodium Bisulfite

Product 1

HCID 19881056HCID 19881056, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

To a solution of 3.4 g of 4-(4-chlorobutyl)-2,3-dihydrothieno[3,2-f]-1,4-thiazepin-5(4H)-one in 100 ml of formic acid was added 2.9 ml of 30% hydrogen peroxide and the mixture was stirred for 3 hours at room temperature. Then, the mixture was poured into ca. 3% sodium hydrogensulfite solution and extracted with chloroform. The extract was washed with water, dried over magnesium sulfate and the solvent was distilled off to give 3.5 g of 4-(4-chlorobutyl)-2,3-dihydrothieno-[3,2-f]1,4-thiazepin-5(4H)-one 1,1-dioxide as a pale yellow oil.

Workup

  1. extractionextracted with chloroform
  2. washThe extract was washed with water
  3. dry with materialdried over magnesium sulfate
  4. distillationthe solvent was distilled off

Sources & evidence

ORD record
ord-80147613a8ee43edae06fa30b6ebcd06
Source dataset
uspto-grants-1992_08
Patent number
US05141930

Reaction notes

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