Benzyl Alcohol → HCID 11788946, compound

HRID 847620Notes

Reaction equation

HRID 847620 reaction equation
[CH:1]([C:4](=[CH2:8])[C:5]([OH:7])=[O:6])([CH3:3])[CH3:2].C1(N=C=NC2CCCCC2)CCCCC1.[CH2:24](O)[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>CCOCC.CN(C)C1C=CN=CC=1>[CH:1]([C:4](=[CH2:8])[C:5]([O:7][CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)=[O:6])([CH3:3])[CH3:2]

Participants

6

Reactant 3

HCID 244Benzyl AlcoholHCID 10868DicyclohexylcarbodiimideHCID 12122615alpha-Isopropylacrylic acid

Product 1

HCID 11788946HCID 11788946, compound

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 3283Diethyl EtherSolvent

Procedure

α-Isopropylacrylic acid (13 mmol) in dry ether (40 ml) was treated with dicyclohexylcarbodiimide (12 mmol), benzyl alcohol (12 mmol) and 4-dimethylaminopyridine (2.5 mmol). After stirring at ambient temperature for 44 h, the mixture was filtered and evaporated. Silica gel chromatography provided the desired compound.

Workup

  1. filtrationthe mixture was filtered
  2. customevaporated

Sources & evidence

ORD record
ord-f456031dd19d466e80dd8f974a02821e
Source dataset
uspto-grants-1992_08
Patent number
US05142056

Reaction notes

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