Acetic Acid → HCID 20566251, compound

HRID 848061Notes

Reaction equation

HRID 848061 reaction equation
[CH:1]([S:4][CH:5]([NH:10][C:11](=[O:22])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18][C:19](=[O:21])[CH3:20])[C:6]([Cl:9])([Cl:8])[Cl:7])([CH3:3])[CH3:2].C(O)(=[O:25])C.OO.O>C(OCC)(=O)C>[CH:1]([S:4]([CH:5]([NH:10][C:11](=[O:22])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[O:18][C:19](=[O:21])[CH3:20])[C:6]([Cl:7])([Cl:9])[Cl:8])=[O:25])([CH3:3])[CH3:2]

Participants

6

Reactant 4

HCID 176Acetic AcidHCID 784Hydrogen PeroxideHCID 962WaterHCID 20566248HCID 20566248, compound

Product 1

HCID 20566251HCID 20566251, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

To 15.0 g of N-(1-iso-propylthio-2,2,2-trichloroethyl)-2-acetoxybenzamide was added 80 ml of acetic acid and 3.8 g of 35% hydrogen peroxide solution was added dropwise thereto under stirring. Then the reaction was effected at 40°-50° C. for three hours and the reaction mixture was poured into water. 100 ml of ethyl acetate was added thereto and the solution was separated, dried, concentrated, washed and dried again to obtain 12.3 g of N-(1-iso-propylsulfinyl-2,2,2-trichloroethyl)-2-acetoxybenzamide.

Workup

  1. additionwas added dropwise
  2. customthe solution was separated
  3. customdried
  4. concentrationconcentrated
  5. washwashed
  6. customdried again

Sources & evidence

ORD record
ord-ba983dece6e640638be848af573e2d8d
Source dataset
uspto-grants-1981_10
Patent number
US04294835

Reaction notes

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