Diazomethane → Methyl α-(2-benzothiazolylthio)benzeneacetate

HRID 848112Notes

Reaction equation

HRID 848112 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH:11]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:12]([OH:14])=[O:13].[N+](=[CH2:23])=[N-]>C1COCC1>[CH3:23][O:13][C:12](=[O:14])[CH:11]([S:10][C:2]1[S:1][C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=1)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

4

Reactant 2

HCID 9550DiazomethaneHCID 3871316HCID 3871316, compound

Product 1

HCID 54106029Methyl α-(2-benzothiazolylthio)benzeneacetate

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

1 g of 2-(benzothiazol-2-ylthio)-2-phenylacetic acid is dissolved in 20 ml of THF, an ethereal solution of diazomethane is added dropwise until a yellow coloration is produced and the mixture is evaporated to give 2-(benzothiazol-2-ylthio)-2-phenylacetic acid methyl ester, in the form of an oil.

Workup

  1. customis produced
  2. customthe mixture is evaporated

Sources & evidence

ORD record
ord-f533ebbf28634df398ccea1fbf32eaee
Source dataset
uspto-grants-1981_10
Patent number
US04294839

Reaction notes

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