Ethanol → HCID 20564189, compound

HRID 848743Notes

Reaction equation

HRID 848743 reaction equation
[C:1]([C:4]1[CH:5]=[CH:6][C:7]2[O:18][C:11]3[NH:12][C:13](=[S:17])[NH:14][C:15](=[O:16])[C:10]=3[CH2:9][C:8]=2[CH:19]=1)([OH:3])=[O:2].[CH2:20](O)[CH3:21]>Cl>[CH2:20]([O:2][C:1]([C:4]1[CH:5]=[CH:6][C:7]2[O:18][C:11]3[NH:12][C:13](=[S:17])[NH:14][C:15](=[O:16])[C:10]=3[CH2:9][C:8]=2[CH:19]=1)=[O:3])[CH3:21]

Participants

4

Reactant 2

HCID 702EthanolHCID 20564185HCID 20564185, compound

Product 1

HCID 20564189HCID 20564189, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

Suspend 7-carboxy-(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione (5 g.) in ethanol and pass in HCl gas until saturated. Reflux the mixture for 24 hours then cool, filter and wash with ethanol and ether to yield 7-ethoxycarbonyl(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione.

Workup

  1. temperatureReflux the mixture for 24 hours
  2. temperaturethen cool
  3. filtrationfilter
  4. washwash with ethanol and ether

Sources & evidence

ORD record
ord-8b4a2aadaeb5419c99c0822f92f09363
Source dataset
uspto-grants-1981_10
Patent number
US04297355

Reaction notes

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