反应详情

A solution of 3.63 g (14.9 mmol) of 1,2-dihydro-6-nitro-2-oxo-3-quinolinecarboxylic acid and 200 ml of dimethylformamide is hydrogenated using 1 g of Raney nickel catalyst at 52 psi and 23° until the required amount of hydrogen uptake is obtained. The catalyst is filtered off and the filtrate is evaporated to dryness. The residue is treated with ethanol and 3.0 g of the desired product is filtered.

1. customat 52 psi and 23°
2. customis obtained
3. filtrationThe catalyst is filtered off
4. customthe filtrate is evaporated to dryness
5. additionThe residue is treated with ethanol and 3.0 g of the desired product
6. filtrationis filtered