Hydrochloric Acid → HCID 13139543, compound

HRID 851159Notes

Reaction equation

HRID 851159 reaction equation
[CH2:1]([O:4][C:5](=[O:26])[C@H:6]([NH:19][C:20]([O:22][CH2:23][CH:24]=[CH2:25])=[O:21])[CH2:7][S:8]SC[C@@H](N)C(OCC=C)=O)[CH:2]=[CH2:3].Cl>CO.[Zn]>[CH2:1]([O:4][C:5](=[O:26])[C@@H:6]([CH2:7][SH:8])[NH:19][C:20]([O:22][CH2:23][CH:24]=[CH2:25])=[O:21])[CH:2]=[CH2:3]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 86738862HCID 86738862, compound

Product 1

HCID 13139543HCID 13139543, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 887MethanolSolvent

Procedure

A suspension of zinc dust (5.18 g) in a solution of bis(N-allyloxycarbonyl-D-cystine bis-allyl ester (5.18 g) in methanol (50 ml) at 0° C. is stirred vigorously while adding concentrated hydrochloric acid (3.5 ml) in one portion. After two minutes, the mixture is worked up as in the above Preparation B to afford the title product.

Workup

  1. customthe mixture is worked up as in the above Preparation B

Sources & evidence

ORD record
ord-d5563e9fa2cd4ce2b75da9ea83bf2cbf
Source dataset
uspto-grants-1983_05
Patent number
US04382949

Reaction notes

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